Elevating movement;
reprogramming the mind.

Smart Rehabilitation Powered By Upper Extremity Science

Achieving patient recovery through adaptive neurorehabilitation based on proprietary Error Augmentation technology

Our innovation lies in the combination of a new approach to motor learning and groundbreaking technology.

A unique robotic device applies motor error augmentation forces that operate during practice in a virtual 3D environment.  The forces trigger the body's instinctive adaptive response, which does not require the use of cognition to correct the movement.

  • A simulated environment enhances patient motivation and participation.
  • Gamified tasks act as a great indicator of treatment progression for patients on their way to recovery.
  • Error augmentation forces lead patients to instinctively correct their own movements with zero reliance on manual guidance
Takeaways
~4x
Improvement in MAS with Error Augmentation vs. without
14.8%
More movement precision with Error Augmentation
2x
Improvement in Fugl-Meyer (FM) scores with Error Augmentation

Built on Clinical Evidence

Clinical research supports error-augmentation as an effective strategy for improving upper-limb motor recovery following neurological injury.

Studies in robotic rehabilitation show that amplifying movement errors can accelerate motor learning by driving adaptive updates to the brain’s internal movement models, resulting in improved movement performance and recovery outcomes.

Across multiple clinical studies, error-augmentation training has been shown to improve upper-extremity motor performance compared with conventional repetitive practice in post-stroke rehabilitation.

Liu, L.Y., Li, Y. & Lamontagne, A. The effects of error-augmentation versus error-reduction paradigms in robotic therapy to enhance upper extremity performance and recovery post-stroke: a systematic review.J NeuroEngineering Rehabil15, 65 (2018).

"Backed by two decades of research, Error Augmentation has demonstrated significant advantages over repetitive practice alone in randomized controlled trials for motor recovery."
Dr. James L. Patton, PhD
Senior Research Scientist and Professor of Engineering

Read all about our science based technology

Motor Improvement by Error Augmentation Forces

Our upper extremity rehabilitation methodology was inspired by two key findings:

The brain predicts forces that are necessary for an upcoming movement and programs muscle activation accordingly

When force prediction is incorrect, movement errors drive adaption of the motor commands

The adaptive instinct that occurs for changes in environmental forces is called 'After Effect', representing the change that has been made in movement patterns. We've harnessed this adaptive instinctive force response to create our unique movement error therapy:
Adaptive Learning

Patients perform a movement with an error; the system measures the movement.

Force Application

Error-augmenting force is applied, continuously adapted by machine learning based on the patient’s session performance.

Error Augmentation

Augmented error triggers adaptive patient response. Nervous system instinctively corrects movement pattern in real time.

Motor Pathway
Reinforcement

Repeated corrective responses reinforce neural motor pathways, strengthening movement control and coordination.

Long-Term Motor Consolidation

Internal model is reactivated and motor memory consolidated, enabling durable, efficient, long-term movement patterns.

Hear from healthcare professionals and patients whose lives have been transformed by Bioxtreme technology

Shiran Yakobovitch - Dahari
Reuth Rehabilitation Hospital

"Dextreme™ gives the therapist the ability to control the amount of help given to each patient according to their needs. I can clearly see the improvement in arm functionality after using the system."

Dr. Franco Molteni
Director Physical Medicine and Rehabilitation Department Villa Beretta Rehabilitation Centre, Valduce Hospital

“Bioxtreme exercises control by means of precise Error Augmentation, which is a smart way of innovation that provides patients with an excellent training path.”

Luigi Satragno
Patient, Villa Beretta Rehabilitation Center

"I find Dextreme™ extremely smart as it stimulates the need for the movement and allows me to understand the importance as well as the perception of correct movements."

Our rehabilitation solutions

Transform your Rehabilitation Program

For further information about the Dextreme™ device, Plaxtreme, and our neurorehabilitation therapeutic solutions