Elevating movement;
reprogramming the mind.

Where Error Becomes Independence

Experience the difference with Bioxtreme:
the only Error Augmentation based technology for upper limb rehabilitation, engineered for better outcomes.

Proven Results
Clinically Validated

Transforming rehabilitation outcomes, one error at a time.

Bioxtreme’s proprietary error augmentation platform is the only technology of its kind redefining rehabilitation outcomes worldwide.

Up to
40%
improvement in upper limb function * in 5 years
Up to
14.8%
reduction in hand trajectory errors
Up to
10+
Years Research
Up to
4X
improvement in MAS 
vs. standard robotic therapy

Error Augmentation amplifies movement errors to trigger the brain’s natural adaptive responses, accelerating motor learning and improving movement accuracy.

Without Error Augmentation
Using Error Augmentation

State-of-the-Art Rehabilitation Devices designed to accelerate recovery & restore independence

Plaxtreme

Precision robotic therapy for hands and fingers. Restore functional grasp, release, and rotational control through Bioxtreme's proven error augmentation technology.

KEY FEATURES
  • Easy set-up / calibration
  • Task-based grasp and release therapy
  • Supination and pronation training
  • AI-driven personalized therapy
  • Adjustable therapy protocols
More than
2x

Improvement in upper-limb motor function (ARAT score) after treatment with Plaxtreme vs. standard robotic therapy, with the same number of treatment sessions.*

100%

Pinch strength improvement following treatment with Plaxtreme, compared to standard robotic therapy*. **

*robotic therapy without Error Augmentation forces
**preliminary results based on ongoing clinical trial

Dextreme™

Advanced robotic rehabilitation for shoulders, elbows, and arms. Accelerate motor recovery with proven error augmentation technology.

KEY FEATURES
  • Easy set-up / calibration
  • Full arm range of motion training
  • AI-driven personalized therapy
  • Customizable therapy protocols
  • Clinically validated results
Superior outcomes
6 sessions

After only 6 sessions with Dextreme™ for individuals post stroke compared to standard robotic therapy

2x

Improvement in Fugl-Meyer scores with Dextreme™ training for individuals post stroke vs. standard robotic therapy

*compared to standard robotic therapy outcomes

Experience the Difference

Discover detailed specifications, clinical evidence, and how our proprietary Error Augmentation technology can transform your rehabilitation program

Share Gains Across the Care Ecosystem

Better tools for care teams. Better progress for patients. Greater confidence for families. Rehabilitation works best when everyone is supported.

Healthcare Facilities
  • Enhanced patient outcomes
  • Improved efficiency
  • Seamless integration of advanced rehabilitation technology into clinical workflows
Patients & Families
  • Faster recovery to independence
  • Improved quality of life
  • Gamified 3D patient experience
Therapists
  • Data-driven treatment plans
  • Higher patient engagement
  • Professional satisfaction

Transforming rehabilitation challenges into recovery success. Bioxtreme addresses the critical challenges in stroke rehabilitation with innovative technology

CHALLENGE
Slow Recovery Times

Traditional rehabilitation methods can take months or years with limited progress

Solution
Rapid Clinical Gains

Error Augmentation technology demonstrates clinically significant motor improvements in just 2 weeks for individuals post stroke

CHALLENGE
Plateaued Progress

Patients often reach a recovery plateau with conventional therapy techniques

Solution
Sustained Performance Improvement

Multi-directional practice with Error Augmentation forces promotes improved motor performance

CHALLENGE
Limited Motor Recovery

Incomplete restoration of fine motor skills and dexterity affects quality of life

Solution
Restoration-Driven Recovery.

Our Error Augmentation therapy facilitates restorative motor relearning to support functional independence

TRANSFORM YOUR rehabilitation OUTCOMES

Discover how Bioxtreme's innovative technology can accelerate recovery for your patients.

Revolutionary technology that goes beyond traditional rehabilitation to deliver unprecedented results

Traditional Therapy
vs.
Bioxtreme Therapy
Focuses on error correction
Magnifies errors to enhance learning
Slower neural adaptation and learning
Nearly 2X improvement in Fugl-Meyer scores with Dextreme™ training vs. standard robotic therapy for individuals post stroke
Limited recovery past initial plateau
Breaks through recovery plateaus
Error Augmentation Technology

Unlike traditional methods that reduce errors, our groundbreaking approach magnifies them to accelerate neural learning and motor recovery

Our patented error augmentation technology works by strategically amplifying movement errors during therapy sessions.

This counterintuitive approach triggers enhanced neural plasticity and motor learning, resulting in 100% additional improvement compared to error reduction methods. The brain learns faster when forced to adapt to and correct magnified errors.

Clinical Precision

Advanced robotics provide precise, controlled movements that target specific upper extremity movement patterns and neural pathways for optimal recovery

Our robotic systems deliver millimeter-precise movements and force feedback, allowing therapists to target specific muscle groups, joints, and neural pathways. Real-time adjustments ensure optimal challenge levels for each patient, maximizing neuroplasticity and functional recovery outcomes.

Measurable Outcomes

Real-time data tracking shows significant improvement compared to conventional rehabilitation methods

Every therapy session generates detailed performance metrics including range of motion, force output, movement accuracy, and progress trends. Our analytics dashboard provides therapists with actionable insights to optimize treatment plans and demonstrate ROI to stakeholders.

Research-Backed Innovation

10+ years of research and various clinical studies validate the effectiveness of proprietary error augmentation approach

Founded on groundbreaking research from Northwestern University and validated through extensive clinical trials across Europe and North America. Our technology is supported by peer-reviewed publications in leading journals and endorsed by leading rehabilitation researchers worldwide.

Safe & Non-Invasive

FDA-cleared medical devices designed with patient safety as the top priority, suitable for various stages of recovery

Our devices meet the highest safety standards with FDA clearance, CE marking, and ISO 13485 certification. Multiple safety features including emergency stops, force limiters, and patient monitoring ensure risk-free therapy sessions for patients at all recovery stages.

Patient-Centered Design

Intuitive interfaces and comfortable ergonomics ensure therapy sessions are effective and engaging for patients

Designed in collaboration with therapists and patients, our systems feature adjustable positioning, comfortable padding, intuitive controls, and engaging visual feedback. Patients report high satisfaction and motivation to complete therapy sessions.

Hear from healthcare professionals and patients whose lives have been transformed by Bioxtreme technology

Shiran Yakobovitch - Dahari
Reuth Rehabilitation Hospital

"Dextreme™ gives the therapist the ability to control the amount of help given to each patient according to their needs. I can clearly see the improvement in arm functionality after using the system."

Dr. Franco Molteni
Director Physical Medicine and Rehabilitation Department Villa Beretta Rehabilitation Centre, Valduce Hospital

“Bioxtreme exercises control by means of precise Error Augmentation, which is a smart way of innovation that provides patients with an excellent training path.”

Luigi Satragno
Patient, Villa Beretta Rehabilitation Center

"I find Dextreme™ extremely smart as it stimulates the need for the movement and allows me to understand the importance as well as the perception of correct movements."

Our rehabilitation solutions

Transform your Rehabilitation Program

For further information about the Dextreme™ device, Plaxtreme, and our neurorehabilitation therapeutic solutions